Monday, July 24, 2017

Oxigene Nears Marketing Approval of First Anaplastic Thyroid Cancer Drug

Dissertation Sur Le Sport Et La Sant With just a few weeks left on the calendar before the world’s largest oncology annual meeting, investors are already gearing up their portfolios for equities that could see exponential gains based on their potentially new research abstracts. The American Society of Clinical Oncology (ASCO) will begin on June 3rd and will feature everything from investigational new drugs to well developed late-stage products. While many companies have seen strong share appreciation leading up to their presentations, the real key lies in finding companies like Oxigene (NASDAQ:OXGN) which has yet to experience this momentum and mass media coverage.

At a market cap of only 10M, Oxigene remains the cheapest and most undervalued of all phase 3 late-stage oncology companies worldwide, with its flagship product, ZYBRESTAT targeting Tanaplastic Thyroid Cancer. The company has stated that they will be presenting the final phase 2/3 (FACT study) data for the drug at the ASCO, and many experts seem to be leaning towards highly positive results based on its previous clinical trials. Currently there exists no treatments available for this form of cancer other than radiation therapy and surgery which is usually combined with chemotherapy.

Dissertation Help Services Just a few months ago, the company reported positive data from the FACT study of ZYBRESTAT plus chemotherapy in patients with Anaplastic thyroid cancer (ATC). At the 14th International Thyroid Congress,  the company’s investigators reported that patients receiving ZYBRESTAT had a median overall survival (OS) time of 5.1 months, compared with a median survival time of 4.1 months for patients receiving chemotherapy alone. Furthermore, 48% of patients treated with ZYBRESTAT and chemotherapy were alive at six months, compared with 37% percent of patients treated with only chemotherapy and at one year, 23% of patients treated with ZYBRESTAT and chemotherapy were alive compared to 9% of patients treated with chemotherapy alone. These are some of the best results of any late-stage Aanaplastic thyroid cancer drugs seen worldwide, and this improvement in OS is meaningful, both clinically and on a personal level for patients. With no currently approved drugs in the market for treatment, the doors are wide open for Oxigene to step in and dominate it. The company also reported on March 21st that they had spoken with the FDA and received very positive type C meeting minutes stating that the trial data was highly suggestive of regulatory approval given an additional clinical trial with a suvival endpoint.

Business Plan Customer Service Policy The Thyroid cancer market was estimated to be worth $55M in 2010, and is expected to grow at a CAGR (Compound Annual Growth Rate) of 27.34% to reach $298M by 2017.

Homework Help App Android Oxigene will also be presenting their additional phase 2 (FALCON study) data also for ZYBRESTAT for the treatment of Non-small cell lung cancer at the ASCO. The FALCON study is the first randomized, controlled study of a vascular disrupting agent (VDA) in combination with an anti-angiogenic agent, and combined both bevacizumab and chemotherapy. In mid-2010, the company reported that to date, the drug was well-tolerated, and the clinical activity they are seeing  indicates a trend toward clinical benefit. These data are still interim; and the final overall survival data from this study will be presented at the ASCO.

According to a new report by Global Industry Analysts, the global Non-small cell lung cancer therapeutics market is slated to reach $13.3 billion by 2015. This is largely fueled by rising incidence of lung cancer, improved understanding of non-small cell lung cancer, and the development of new treatments targeted at growth factor pathways.

Additionally, the company features a diverse pipeline with a total of 7 indications, potentially targetting a market of $5 billion or more, should a few of these meet FDA marketing approval. With mergers and acquisitions being a hot topic within the biotech industry as larger companies look to strengthen their portfolios, the expectation of a partnership also remains highly probable in 2011, and according to the CEO’s open letter, Mr. Langecker, “The feedback we’ve gathered from potential partners is that we now have a stronger collection of data validating proof of concept. We believe that there is meaningful interest among potential partners in pursuing a possible collaboration.”

The recent decline in price can be attributed to and equity offering agreement with McNicoll, Lewis & Vlak LLC, or MLV, that saw the company raise approximately $8,776,000 in order to strengthen its balance sheet from July 21, 2010 to date. The company has stated that as the current ongoing trials proceed to completion, they expect the per quarter cash requirement to continue to decline to the $2,500,000 to $3,000,000 range over the course of 2011, thus it can be assumed that based on the previous financing, a healthy state on its balance sheet has now been achieved for the time being. All information per the 10-K filing as of 3/16/2011.

Live Homework Help Alabama Technical Analysis

Since the start of 2011, Oxigene’s shares have been stuck in a constant downtrend that saw a minor attempt and failure to breakout during early February and late March. Despite positive clinial developments, shares were hit by the financing news which took the stock down from the mid $5 range all the way to the present mid $1, presenting a highly favourable risk versus reward ratio. The stock seems to be basing as the downtrend looks to finish, and a break past the $2.25 resistance could mark a reversal of the price action towards the upside.

The first resistance lies at the 50-day moving average of $2.25, which also incidentally conicides with a previous basing attempt, and should this be broken, there is clear break to the $4-4.50 level which is also the 200-day moving average. The RSI seems to be gaining momentum as buying pressure once again resumes in the equity, which is also supported by a positive MACD divergence currently engaged in a bullish cross. Look for stock to gain momentum as anticipation builds in the coming weeks ahead of  highly anticipated positive developments during ASCO conference.

Disclosure: Long OXGN


[[T_F]]Data Leak Prevention – Data Security Solutions – Information Theft Protection, Detection and Prevention Software Productstracefusion_signature=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[[T_F]]

Tags: , , ,

| More

32 Responses for “Oxigene Nears Marketing Approval of First Anaplastic Thyroid Cancer Drug”

  1. Jonas says:

    What do you think about the warrent with death spiral. Meaning why did Oxigene give a way free shares to cancel those warrent.. Is it maybe to get buyers on the table.
    Jonas – Denmark.

  2. Brandon says:

    Do it, do it now. Mid may will get your money back as people invest in anticipation, if you want to play it out and risk being in for its FDA approval it could very well skyrocket, and current information looks promising. I want this approved, anything that gives terminal cancer patients longer to be treated, and helps them out is worth a shot. Big dollar potential in the near future is a nice perk.

  3. exMBB says:

    5.1 months vs. 4.1 months? The p value must be pretty crappy

  4. Howdy! Do you know if they make any plugins to help with SEO?
    I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good results.
    If you know of any please share. Thanks!

  5. says:

    It’s going to be end of mine day, but before finish I am reading this wonderful article to increase my experience.

  6. Good post but I was wanting to know if you could write a litte more on this topic?
    I’d be very grateful if you could elaborate a little bit further. Cheers!

    Here is my web blog Immigration Lawyers in Hackney

  7. If some one needs expert view regarding blogging and
    site-building afterward i advise him/her to pay a quick visit this webpage, Keep up
    the pleasant work.

  8. Hi there, its nice article concerning media print, we all be familiar with media is
    a fantastic source of information.

  9. adult toys says:

    Thank you a bunch for sharing this with all folks you actually know what you’re talking approximately! Bookmarked. Please also visit my web site =). We will have a link exchange contract between us

  10. First of all I would like to say terrific blog!
    I had a quick question that I’d like to ask if you do not mind. I was interested to know how you center yourself and clear your thoughts before writing. I have had trouble clearing my mind in getting my thoughts out. I truly do enjoy writing however it just seems like the first 10 to 15 minutes are generally wasted simply just trying to figure out how to begin. Any recommendations or tips? Cheers!

  11. I think everything said was very reasonable. However, what about this?
    what if you composed a catchier title? I ain’t saying your content isn’t good, however what if you added a title that makes
    people want more? I mean Oxigene Nears Marketing Approval of First Anaplastic Thyroid Cancer Drug | The Market Financial | Stock Market & Wall
    Street News is kinda plain. You could glance at Yahoo’s home page and note how they create article headlines to grab viewers to click. You might try adding a video or a picture or two to get readers excited about what you’ve written.
    In my opinion, it might bring your posts a
    little livelier.

  12. I hardly drop comments, however I looked at some of the responses on this page Oxigene Nears Marketing Approval of First Anaplastic Thyroid Cancer
    Drug | The Market Financial | Stock Market
    & Wall Street News. I do have a couple of questions for you if you don’t mind. Is it only me or does it look as if like some of these remarks come across like they are coming from brain dead folks? 😛 And, if you are posting on additional online sites, I would like to keep up with you. Could you make a list of every one of all your social sites like your linkedin profile, Facebook page or twitter feed?

  13. If you would like to improve your know-how simply keep visiting this web
    page and be updated with the newest information posted here.

  14. WOW just what I was looking for. Came here by searching for pageant crowns large

  15. Thanks for the marvelous posting! I really enjoyed reading it,
    you can be a great author. I will ensure that I bookmark your blog and will often come back down the road.
    I want to encourage you to continue your great posts, have a nice holiday weekend!

  16. Add spices appropriately: If you are using whole spices (recommended), add them at the beginning of
    cooking. Often, a recipe will ask that you cook a meal 3-4
    hours on the “high” setting, or 6-8 hours on “low”.
    There are no real features to speak of, as the Slow Cooker market is somewhat unsophisticated.

  17. I always was interested in this subject and still am, thanks for posting .

  18. I think that is one of the so much important info for me.
    And i’m glad studying your article. However wanna remark on some normal things, The site style is great, the articles is in reality nice : D. Good process, cheers

  19. Hello there! Quick question that’s entirely off topic. Do you know how to make your site mobile friendly? My web site looks weird when viewing from my iphone 4. I’m trying to find
    a template or plugin that might be able to resolve this issue.

    If you have any suggestions, please share. Thanks!

  20. I’ve read several good stuff here. Definitely worth bookmarking for revisiting. I wonder how so much attempt you put to create this type of wonderful informative web site.

  21. I absolutely love your blog and find most of your post’s to be what precisely I’m looking for. can you offer guest writers to write content available for you? I wouldn’t mind producing a post or elaborating on a lot of the subjects you write about here. Again, awesome site!

  22. I would LOVE to join in for a Spring Swap!!!! PS. You give the best gifts

  23. Great post. I was checking constantly this blog and
    I am impressed! Extremely useful information specially the last part 🙂 I care
    for such info much. I was looking for this particular info for a
    very long time. Thank you and best of luck.

    Also visit my web site: ASUS VS278Q-P Review

  24. Heya i’m for the primary time here. I found this board and I in finding It really helpful & it helped me out much. I am hoping to provide one thing back and help others like you aided me.

  25. katowice says:

    Parking oddalony jest o ok. 200m od Międzynarodowego Portu Lotniczego “Katowice”.

  26. ペンションサンドリヨンのルイヴィトンコピーベルトモール/アウトドア「ペンションサンドリヨンのスーパーコピールイヴィトン財布モール」(以下、「本サイト」と云います)の閲覧は、本サイトにアクセスしご覧になる方の自己責任において行ってください本サイトは、アフィリエイトプログラムを利用しています。

  27. I do agree with all of the ideas you’ve offered for your post.
    They are really convincing and can certainly work.
    Nonetheless, the posts are very short for novices.
    May just you please prolong them a bit from next time?
    Thanks for the post.

  28. x lander xa says:

    It’s wonderful that you are getting thoughts from this paragraph as well as from our
    argument made at this place.

  29. My family always say that I am killing my time here
    at web, except I know I am getting familiarity every day by reading
    thes good articles or reviews.

  30. Thanks for the good writeup. It actually used to be a
    enjoyment account it. Look advanced to far brought agreeable from you!
    However, how could we keep in touch?

  31. The Electric Scooters are generally equipped with advanced brake systems which
    make the stopping of these scooters very simple. This is definitely great
    some people will plan iin order to drive the scooters to figureout.
    If you buy onne tht just barely covers the weight load; the sccooter will be
    under constant strain and mmay not laswt as
    long as you would like.

    Feel free too visit my homepage; 2 Wheel Motorized Balance Scooter

Comments are closed

Back to Top

Social Media Profiles



The New York Times logo CNN logo ABC logo CNBC logo